Engineering Lactococcus lactis as a multi-stress tolerant biosynthetic chassis by deleting the prophage-related fragment

Engineering Lactococcus lactis as a multi-stress tolerant biosynthetic chassis by deleting the prophage-related fragment

Abstract Background In bioengineering, growth of microorganisms is limited because of environmental and industrial stresses during fermentation. This study aimed to construct a nisin-producing chassis Lactococcus lactis strain with genome-streamlined, low metabolic burden, and multi-stress tolerance...

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Bibliographic Details
Main Authors: Wanjin Qiao, Yu Qiao, Fulu Liu, Yating Zhang, Ran Li, Zhenzhou Wu, Haijin Xu, Per Erik Joakim Saris, Mingqiang Qiao
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Microbial Cell Factories
Subjects:
Lactococcus lactis
Prophage-related fragment
Genome editing
Multi-stress tolerance
Nisin immunity
Nisin yield
Online Access:https://doi.org/10.1186/s12934-020-01487-x

Internet

https://doi.org/10.1186/s12934-020-01487-x

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