Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of Ccn2

Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of Ccn2

CCN2 is a matricellular protein involved in several crucial biological processes. In particular, CCN2 is involved in cartilage development and in osteoarthritis. Ccn2 null mice exhibit a range of skeletal dysmorphisms, highlighting its importance in regulating matrix formation during development; ho...

Full description

Bibliographic Details
Main Authors: Craig M. Keenan, Lorenzo Ramos-Mucci, Ioannis Kanakis, Peter I. Milner, Andrew Leask, David Abraham, George Bou-Gharios, Blandine Poulet
Format: Article
Language:English
Published: The Company of Biologists 2020-07-01
Series:Disease Models & Mechanisms
Subjects:
cartilage
ccn2
osteoarthritis
post-traumatic
transgenic mouse
trauma-induced
Online Access:http://dmm.biologists.org/content/13/7/dmm044719

Internet

http://dmm.biologists.org/content/13/7/dmm044719

Similar Items