The macrophage-derived protein PTMA induces filamentation of the human fungal pathogen Candida albicans

The macrophage-derived protein PTMA induces filamentation of the human fungal pathogen Candida albicans

Summary: Evasion of killing by immune cells is crucial for fungal survival in the host. For the human fungal pathogen Candida albicans, internalization by macrophages induces a transition from yeast to filaments that promotes macrophage death and fungal escape. Nutrient deprivation, alkaline pH, and...

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Bibliographic Details
Main Authors: Nicola T. Case, Kwamaa Duah, Brett Larsen, Cassandra J. Wong, Anne-Claude Gingras, Teresa R. O’Meara, Nicole Robbins, Amanda O. Veri, Luke Whitesell, Leah E. Cowen
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Cell Reports
Subjects:
hyphae
morphogenesis
fungi
host-pathogen interaction
phagosome
Candida albicans
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721010184

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http://www.sciencedirect.com/science/article/pii/S2211124721010184

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