Interleukin-10 deficiency exacerbates inflammation-induced tau pathology
Abstract Background The presence of hyperphosphorylated microtubule-associated protein tau is strongly correlated with cognitive decline and neuroinflammation in Alzheimer’s disease and related tauopathies. However, the role of inflammation and anti-inflammatory interventions in tauopathies is uncle...
Main Authors: | Lea L. Weston, Shanya Jiang, Devon Chisholm, Lauren L. Jantzie, Kiran Bhaskar |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-07-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-021-02211-1 |
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