A generic cell surface ligand system for studying cell-cell recognition.

Dose-response experiments are a mainstay of receptor biology studies and can reveal valuable insights into receptor function. Such studies of receptors that bind cell surface ligands are currently limited by the difficulty in manipulating the surface density of ligands at a cell-cell interface. Here...

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Bibliographic Details
Main Authors: Eleanor M Denham, Michael I Barton, Susannah M Black, Marcus J Bridge, Ben de Wet, Rachel L Paterson, P Anton van der Merwe, Jesse Goyette
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000549