High CD206 levels in Hodgkin lymphoma‐educated macrophages are linked to matrix‐remodeling and lymphoma dissemination

High CD206 levels in Hodgkin lymphoma‐educated macrophages are linked to matrix‐remodeling and lymphoma dissemination

Macrophages (Mφ) are abundantly present in the tumor microenvironment and may predict outcome in solid tumors and defined lymphoma subtypes. Mφ heterogeneity, the mechanisms of their recruitment, and their differentiation into lymphoma‐promoting, alternatively activated M2‐like phenotypes are still...

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Bibliographic Details
Main Authors: Annekatrin Arlt, Frederike vonBonin, Thorsten Rehberg, Paula Perez‐Rubio, Julia C. Engelmann, Katharina Limm, Sarah Reinke, Christian Dullin, Xueni Sun, Rieke Specht, Markus Maulhardt, Franziska Linke, Gertrude Bunt, Wolfram Klapper, Martina Vockerodt, Jörg Wilting, Tobias Pukrop, Katja Dettmer, Wolfram Gronwald, Peter J. Oefner, Rainer Spang, Dieter Kube
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Molecular Oncology
Subjects:
CD206
lymphoma
macrophages
tumor microenvironment
Online Access:https://doi.org/10.1002/1878-0261.12616

Internet

https://doi.org/10.1002/1878-0261.12616

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