DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis

DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis

Monozygotic (MZ) twins are ideal to study the influence of non-genetic factors on complex phenotypes. Here, Souren et al. perform an EWAS in peripheral blood mononuclear cells from 45 MZ twins discordant for multiple sclerosis and identify disease and treatment-associated epigenetic markers.

Bibliographic Details
Main Authors: Nicole Y. Souren, Lisa A. Gerdes, Pavlo Lutsik, Gilles Gasparoni, Eduardo Beltrán, Abdulrahman Salhab, Tania Kümpfel, Dieter Weichenhan, Christoph Plass, Reinhard Hohlfeld, Jörn Walter
Format: Article
Language:English
Published: Nature Publishing Group 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09984-3

Internet

https://doi.org/10.1038/s41467-019-09984-3

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