Characterization of histone acylations links chromatin modifications with metabolism

Characterization of histone acylations links chromatin modifications with metabolism

A number of histone lysine modifications related to acetylation have been identified, but their functional significance is unclear. Here, the authors use in vitro and in vivo assays to characterize eight acyl histone post-translational modifications and link their abundance with metabolism.

Bibliographic Details
Main Authors: Johayra Simithy, Simone Sidoli, Zuo-Fei Yuan, Mariel Coradin, Natarajan V. Bhanu, Dylan M. Marchione, Brianna J. Klein, Gleb A. Bazilevsky, Cheryl E. McCullough, Robert S. Magin, Tatiana G. Kutateladze, Nathaniel W. Snyder, Ronen Marmorstein, Benjamin A. Garcia
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01384-9

Internet

https://doi.org/10.1038/s41467-017-01384-9

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