Randomized, phase II trial of sequential hepatic arterial infusion chemotherapy and sorafenib versus sorafenib alone as initial therapy for advanced hepatocellular carcinoma: SCOOP-2 trial

Randomized, phase II trial of sequential hepatic arterial infusion chemotherapy and sorafenib versus sorafenib alone as initial therapy for advanced hepatocellular carcinoma: SCOOP-2 trial

Abstract Background The efficacy of hepatic arterial infusion chemotherapy (HAIC) for advanced hepatocellular carcinoma (HCC) remains unclear. We conducted a multi-center randomized phase II study comparing a sequential HAIC-sorafenib regimen versus sorafenib alone as an initial therapy for HCC. Met...

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Bibliographic Details
Main Authors: Masaaki Kondo, Manabu Morimoto, Satoshi Kobayashi, Shinichi Ohkawa, Hisashi Hidaka, Takahide Nakazawa, Hiroshi Aikata, Takeshi Hatanaka, Daichi Takizawa, Kotaro Matsunaga, Chiaki Okuse, Michihiro Suzuki, Masataka Taguri, Takako Ishibashi, Kazushi Numata, Shin Maeda, Katsuaki Tanaka
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Cancer
Subjects:
Hepatocellular carcinoma
Hepatic arterial infusion chemotherapy
Cisplatin
Sorafenib
Sequential treatment
Online Access:http://link.springer.com/article/10.1186/s12885-019-6198-8

Internet

http://link.springer.com/article/10.1186/s12885-019-6198-8

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