NLRP3 Inflammasome: a New Pharmacological Target for Reducing Testicular Damage Associated with Varicocele

NLRP3 Inflammasome: a New Pharmacological Target for Reducing Testicular Damage Associated with Varicocele

Many bioactive natural compounds are being increasingly used for therapeutics and nutraceutical applications to counteract male infertility, particularly varicocele. The roles of selenium and Polydeoxyribonucleotide (PDRN) were investigated in an experimental model of varicocele, with particular reg...

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Bibliographic Details
Main Authors: Pietro Antonuccio, Antonio Girolamo Micali, Carmelo Romeo, Jose Freni, Giovanna Vermiglio, Domenico Puzzolo, Francesco Squadrito, Natasha Irrera, Herbert R. Marini, Rosa Alba Rana, Giovanni Pallio, Letteria Minutoli
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
varicocele
testis
NLRP3 inflammasome
A<sub>2A</sub> receptor
PDRN
selenium
Online Access:https://www.mdpi.com/1422-0067/22/3/1319

Internet

https://www.mdpi.com/1422-0067/22/3/1319

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