Two loci on chromosome 9 control bile acid composition: evidence that a strong candidate gene, Cyp8b1, is not the culprits⃞

An intercross between C57BL/6J and CASA/Rk mice was used to study the genetics of biliary bile acid composition. In parental strains, male C57BL/6J mice had significantly higher cholic acid (CA; 14%) and lower β-muricholic acid (βMC; 27%) than CASA/Rk mice, whereas females did not differ. However, q...

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Bibliographic Details
Main Authors: Ephraim Sehayek, Lee R. Hagey, Yee-Yan Fung, Elizabeth M. Duncan, Hannah J. Yu, Gösta Eggertsen, Ingemar Björkhem, Alan F. Hofmann, Jan L. Breslow
Format: Article
Language:English
Published: Elsevier 2006-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520434698