Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs

Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs

The mammalian enzyme involved in the final elongation of de novo fatty acid biosynthesis following the building of fatty acids to 16 carbons by fatty acid synthase has yet to be identified. In the process of searching for genes activated by sterol regulatory element-binding protein 1 (SREBP-1) by us...

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Bibliographic Details
Main Authors: Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi, Tomohiro Yoshikawa, Michiyo Amemiya-Kudo, Alyssa H. Hasty, Hiroaki Okazaki, Yoshiaki Tamura, Yoko Iizuka, Ken Ohashi, Jun-ichi Osuga, Akimitsu Takahashi, Shigeru Yato, Hirohito Sone, Shun Ishibashi, Nobuhiro Yamada
Format: Article
Language:English
Published: Elsevier 2002-06-01
Series:Journal of Lipid Research
Subjects:
sterol regulatory element-binding protein
lipogenesis
nutrition
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752030465X

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http://www.sciencedirect.com/science/article/pii/S002222752030465X

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