A transplantable tumor model allowing investigation of NY-BR-1-specific T cell responses in HLA-DRB1*0401 transgenic mice

A transplantable tumor model allowing investigation of NY-BR-1-specific T cell responses in HLA-DRB1*0401 transgenic mice

Abstract Background NY-BR-1 has been described as a breast cancer associated differentiation antigen with intrinsic immunogenicity giving rise to endogenous T and B cell responses. The current study presents the first murine tumor model allowing functional investigation of NY-BR-1-specific immune re...

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Bibliographic Details
Main Authors: Krishna Das, David Eisel, Mathias Vormehr, Karin Müller-Decker, Adriane Hommertgen, Dirk Jäger, Inka Zörnig, Markus Feuerer, Annette Kopp-Schneider, Wolfram Osen, Stefan B. Eichmüller
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Cancer
Subjects:
NY-BR-1
Differentiation antigen
CTL epitope
HLA transgenic mice
Online Access:http://link.springer.com/article/10.1186/s12885-019-6102-6

Internet

http://link.springer.com/article/10.1186/s12885-019-6102-6

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