Cognate Interaction With CD4+ T Cells Instructs Tumor-Associated Macrophages to Acquire M1-Like Phenotype

by David Eisel, David Eisel, David Eisel, Krishna Das, Krishna Das, Krishna Das, Elke Dickes, Rainer König, Wolfram Osen, Stefan B. Eichmüller
Published 2019-02-01

Correction: Generation of murine tumor cell lines deficient in MHC molecule surface expression using the CRISPR/Cas9 system.

by Krishna Das, David Eisel, Clarissa Lenkl, Ashish Goyal, Sven Diederichs, Elke Dickes, Wolfram Osen, Stefan B Eichmüller
Published 2018-01-01

Reprogramming of macrophages employing gene regulatory and metabolic network models.

by Franziska Hörhold, David Eisel, Marcus Oswald, Amol Kolte, Daniela Röll, Wolfram Osen, Stefan B Eichmüller, Rainer König
Published 2020-02-01

Generation of murine tumor cell lines deficient in MHC molecule surface expression using the CRISPR/Cas9 system.

by Krishna Das, David Eisel, Clarissa Lenkl, Ashish Goyal, Sven Diederichs, Elke Dickes, Wolfram Osen, Stefan B Eichmüller
Published 2017-01-01

A transplantable tumor model allowing investigation of NY-BR-1-specific T cell responses in HLA-DRB1*0401 transgenic mice

by Krishna Das, David Eisel, Mathias Vormehr, Karin Müller-Decker, Adriane Hommertgen, Dirk Jäger, Inka Zörnig, Markus Feuerer, Annette Kopp-Schneider, Wolfram Osen, Stefan B. Eichmüller
Published 2019-09-01

561 DuoBody®-PD-L1×4–1BB (GEN1046) induces superior immune-cell activation, cytokine production and cytotoxicity by combining PD-L1 blockade with conditional 4–1BB co-stimulation...

by Maria Jure-Kunkel, Rachelle Kosoff, Mark Fereshteh, Alexander Muik, Isil Altintas, Friederike Gieseke, Kristina Schödel, Theodora Salcedo, Saskia Burm, Aras Toker, Lena Kranz, Mathias Vormehr, David Eisel, Özlem Türeci, Esther Breij, Tahamtan Ahmadi, Ugur Sahin
Published 2020-11-01

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

by Franziska Herster, Zsofia Bittner, Nathan K. Archer, Sabine Dickhöfer, David Eisel, Tatjana Eigenbrod, Thomas Knorpp, Nicole Schneiderhan-Marra, Markus W. Löffler, Hubert Kalbacher, Tim Vierbuchen, Holger Heine, Lloyd S. Miller, Dominik Hartl, Lukas Freund, Knut Schäkel, Martin Heister, Kamran Ghoreschi, Alexander N. R. Weber
Published 2020-01-01