Turning the Tide Against Regulatory T Cells

by SeongJun Han, SeongJun Han, Aras Toker, Zhe Qi Liu, Zhe Qi Liu, Pamela S. Ohashi, Pamela S. Ohashi, Pamela S. Ohashi
Published 2019-04-01

Dynamic Imprinting of the Treg Cell-Specific Epigenetic Signature in Developing Thymic Regulatory T Cells

by Susanne Herppich, Aras Toker, Beate Pietzsch, Yohko Kitagawa, Naganari Ohkura, Takahisa Miyao, Stefan Floess, Shohei Hori, Shohei Hori, Shimon Sakaguchi, Jochen Huehn
Published 2019-10-01

561 DuoBody®-PD-L1×4–1BB (GEN1046) induces superior immune-cell activation, cytokine production and cytotoxicity by combining PD-L1 blockade with conditional 4–1BB co-stimulation...

by Maria Jure-Kunkel, Rachelle Kosoff, Mark Fereshteh, Alexander Muik, Isil Altintas, Friederike Gieseke, Kristina Schödel, Theodora Salcedo, Saskia Burm, Aras Toker, Lena Kranz, Mathias Vormehr, David Eisel, Özlem Türeci, Esther Breij, Tahamtan Ahmadi, Ugur Sahin
Published 2020-11-01

Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer

by Heather L. MacGregor, Carlos Garcia-Batres, Azin Sayad, Andrew Elia, Hal K. Berman, Aras Toker, Sarah Rachel Katz, Patricia A. Shaw, Blaise A. Clarke, Sarah Q. Crome, Celine Robert-Tissot, Marcus Q. Bernardini, Linh T. Nguyen, Pamela S. Ohashi
Published 2019-12-01