Targeting the NLRP3 Inflammasome via BTK

by Alexander N. R. Weber, Alexander N. R. Weber, Alexander N. R. Weber, Alexander N. R. Weber
Published 2021-02-01

Gadd45a is an RNA binding protein and is localized in nuclear speckles.

by Yuliya A Sytnikova, Andriy V Kubarenko, Andrea Schäfer, Alexander N R Weber, Christof Niehrs
Published 2011-01-01

Absence of Non-Canonical, Inhibitory MYD88 Splice Variants in B Cell Lymphomas Correlates With Sustained NF-κB Signaling

by Yamel Cardona Gloria, Yamel Cardona Gloria, Stephan H. Bernhart, Stephan H. Bernhart, Stephan H. Bernhart, Sven Fillinger, Olaf-Oliver Wolz, Olaf-Oliver Wolz, Sabine Dickhöfer, Sabine Dickhöfer, Jakob Admard, Stephan Ossowski, Sven Nahnsen, Reiner Siebert, Reiner Siebert, Alexander N. R. Weber, Alexander N. R. Weber, Alexander N. R. Weber
Published 2021-06-01

Bruton’s Tyrosine Kinase: An Emerging Key Player in Innate Immunity

by Alexander N. R. Weber, Zsofia Bittner, Xiao Liu, Truong-Minh Dang, Markus Philipp Radsak, Cornelia Brunner
Published 2017-11-01

Neutrophils: Between host defence, immune modulation, and tissue injury.

by Philipp Kruger, Mona Saffarzadeh, Alexander N R Weber, Nikolaus Rieber, Markus Radsak, Horst von Bernuth, Charaf Benarafa, Dirk Roos, Julia Skokowa, Dominik Hartl
Published 2015-03-01

Modulation of the CD95-induced apoptosis: the role of CD95 N-glycosylation.

by Olga M Shatnyeva, Andriy V Kubarenko, Claudia E M Weber, Alexander Pappa, Reinhard Schwartz-Albiez, Alexander N R Weber, Peter H Krammer, Inna N Lavrik
Published 2011-01-01

Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of Streptococcus pyogenes in vitro and in vivo

by Anna Hafner, Anna Hafner, Ulrike Kolbe, Isabel Freund, Virginia Castiglia, Pavel Kovarik, Tanja Poth, Franziska Herster, Markus A. Weigand, Alexander N. R. Weber, Alexander H. Dalpke, Alexander H. Dalpke, Tatjana Eigenbrod
Published 2019-02-01

Investigation of single and synergic effects of NLRC5 and PD-L1 variants on the risk of colorectal cancer.

by Calogerina Catalano, Miguel Inacio da Silva Filho, Christoph Frank, Katerina Jiraskova, Veronika Vymetalkova, Miroslav Levy, Vaclav Liska, Ondrej Vycital, Alessio Naccarati, Ludmila Vodickova, Kari Hemminki, Pavel Vodicka, Alexander N R Weber, Asta Försti
Published 2018-01-01

Epistatic effect of TLR3 and cGAS‐STING‐IKKε‐TBK1‐IFN signaling variants on colorectal cancer risk

by Calogerina Catalano, Miguel Inacio daSilva Filho, Christoph Frank, Shun Lu, Katerina Jiraskova, Veronika Vymetalkova, Miroslav Levy, Vaclav Liska, Ondrej Vycital, Alessio Naccarati, Ludmila Vodickova, Kari Hemminki, Pavel Vodicka, Alexander N. R. Weber, Asta Försti
Published 2020-02-01

Study of human RIG-I polymorphisms identifies two variants with an opposite impact on the antiviral immune response.

by Julien Pothlichet, Anne Burtey, Andriy V Kubarenko, Gregory Caignard, Brigitte Solhonne, Frédéric Tangy, Meriem Ben-Ali, Lluis Quintana-Murci, Andrea Heinzmann, Jean-Daniel Chiche, Pierre-Olivier Vidalain, Alexander N R Weber, Michel Chignard, Mustapha Si-Tahar
Published 2009-10-01

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

by Franziska Herster, Zsofia Bittner, Nathan K. Archer, Sabine Dickhöfer, David Eisel, Tatjana Eigenbrod, Thomas Knorpp, Nicole Schneiderhan-Marra, Markus W. Löffler, Hubert Kalbacher, Tim Vierbuchen, Holger Heine, Lloyd S. Miller, Dominik Hartl, Lukas Freund, Knut Schäkel, Martin Heister, Kamran Ghoreschi, Alexander N. R. Weber
Published 2020-01-01

HLA class I-restricted MYD88 L265P-derived peptides as specific targets for lymphoma immunotherapy

by Annika Nelde, Juliane Sarah Walz, Daniel Johannes Kowalewski, Heiko Schuster, Olaf-Oliver Wolz, Janet Kerstin Peper, Yamel Cardona Gloria, Anton W. Langerak, Alice F. Muggen, Rainer Claus, Irina Bonzheim, Falko Fend, Helmut Rainer Salih, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanović, Alexander N. R. Weber
Published 2017-03-01

Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis

by Franziska Herster, Zsofia Bittner, Marius Cosmin Codrea, Nathan K. Archer, Martin Heister, Markus W. Löffler, Markus W. Löffler, Markus W. Löffler, Simon Heumos, Joanna Wegner, Ramona Businger, Michael Schindler, David Stegner, Knut Schäkel, Stephan Grabbe, Kamran Ghoreschi, Kamran Ghoreschi, Lloyd S. Miller, Alexander N. R. Weber
Published 2019-08-01

Flagellin hypervariable region determines symbiotic properties of commensal Escherichia coli strains.

by Alex Steimle, Sarah Menz, Annika Bender, Brianna Ball, Alexander N R Weber, Thomas Hagemann, Anna Lange, Jan K Maerz, Raphael Parusel, Lena Michaelis, Andrea Schäfer, Hans Yao, Hanna-Christine Löw, Sina Beier, Mehari Tesfazgi Mebrhatu, Kerstin Gronbach, Samuel Wagner, David Voehringer, Martin Schaller, Birgit Fehrenbacher, Ingo B Autenrieth, Tobias A Oelschlaeger, Julia-Stefanie Frick
Published 2019-06-01

Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer.

by Stefanie Huhn, Miguel I da Silva Filho, Tharmila Sanmuganantham, Tica Pichulik, Calogerina Catalano, Barbara Pardini, Alessio Naccarati, Veronika Polakova-Vymetálkova, Katerina Jiraskova, Ludmila Vodickova, Pavel Vodicka, Markus W Löffler, Lioba Courth, Jan Wehkamp, Farhat V N Din, Maria Timofeeva, Susan M Farrington, Lina Jansen, Kari Hemminki, Jenny Chang-Claude, Hermann Brenner, Michael Hoffmeister, Malcolm G Dunlop, Alexander N R Weber, Asta Försti
Published 2018-01-01

A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer

by Hans-Georg Rammensee, Karl-Heinz Wiesmüller, P. Anoop Chandran, Henning Zelba, Elisa Rusch, Cécile Gouttefangeas, Daniel J. Kowalewski, Moreno Di Marco, Sebastian P. Haen, Juliane S. Walz, Yamel Cardona Gloria, Johanna Bödder, Jill-Marie Schertel, Antje Tunger, Luise Müller, Maximilian Kießler, Rebekka Wehner, Marc Schmitz, Meike Jakobi, Nicole Schneiderhan-Marra, Reinhild Klein, Karoline Laske, Kerstin Artzner, Linus Backert, Heiko Schuster, Johannes Schwenck, Alexander N. R. Weber, Bernd J. Pichler, Manfred Kneilling, Christian la Fougère, Stephan Forchhammer, Gisela Metzler, Jürgen Bauer, Benjamin Weide, Wilfried Schippert, Stefan Stevanović, Markus W. Löffler
Published 2019-11-01

NLRP3 Inflammasome Assembly in Neutrophils Is Supported by PAD4 and Promotes NETosis Under Sterile Conditions

by Patrick Münzer, Patrick Münzer, Patrick Münzer, Patrick Münzer, Roberto Negro, Roberto Negro, Shoichi Fukui, Shoichi Fukui, Lucas di Meglio, Lucas di Meglio, Lucas di Meglio, Karen Aymonnier, Karen Aymonnier, Karen Aymonnier, Long Chu, Long Chu, Deya Cherpokova, Deya Cherpokova, Sarah Gutch, Sarah Gutch, Nicoletta Sorvillo, Nicoletta Sorvillo, Lai Shi, Lai Shi, Venkat Giri Magupalli, Venkat Giri Magupalli, Alexander N. R. Weber, Rüdiger E. Scharf, Rüdiger E. Scharf, Rüdiger E. Scharf, Clare M. Waterman, Clare M. Waterman, Hao Wu, Hao Wu, Denisa D. Wagner, Denisa D. Wagner, Denisa D. Wagner, Denisa D. Wagner
Published 2021-05-01