Comprehensive mutation analysis in colorectal flat adenomas.

Flat adenomas are a subgroup of colorectal adenomas that have been associated with a distinct biology and a more aggressive clinical behavior compared to their polypoid counterparts. In the present study, we aimed to compare the mutation spectrum of 14 cancer genes, between these two phenotypes.A co...

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Bibliographic Details
Main Authors: Quirinus J M Voorham, Beatriz Carvalho, Angela J Spiertz, Bart Claes, Sandra Mongera, Nicole C T van Grieken, Heike Grabsch, Martin Kliment, Bjorn Rembacken, Mark A van de Wiel, Philip Quirke, Chris J J Mulder, Diether Lambrechts, Manon van Engeland, Gerrit A Meijer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3407043?pdf=render