A Francisella mutant in lipid A carbohydrate modification elicits protective immunity.

Francisella tularensis (Ft) is a highly infectious gram-negative bacterium and the causative agent of the human disease tularemia. Ft is designated a class A select agent by the Centers for Disease Control and Prevention. Human clinical isolates of Ft produce lipid A of similar structure to Ft subsp...

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Bibliographic Details
Main Authors: Duangjit Kanistanon, Adeline M Hajjar, Mark R Pelletier, Larry A Gallagher, Thomas Kalhorn, Scott A Shaffer, David R Goodlett, Laurence Rohmer, Mitchell J Brittnacher, Shawn J Skerrett, Robert K Ernst
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18266468/?tool=EBI