Chromosomal Translocations in the Parasite Leishmania by a MRE11/RAD50-Independent Microhomology-Mediated End Joining Mechanism.

The parasite Leishmania often relies on gene rearrangements to survive stressful environments. However, safeguarding a minimum level of genome integrity is important for cell survival. We hypothesized that maintenance of genomic integrity in Leishmania would imply a leading role of the MRE11 and RAD...

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Bibliographic Details
Main Authors: Marie-Claude N Laffitte, Philippe Leprohon, Maripier Hainse, Danielle Légaré, Jean-Yves Masson, Marc Ouellette
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4912120?pdf=render