Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight

Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight

The obesity epidemic is a significant global health issue. Improved understanding of the mechanisms that regulate appetite and body weight will provide the rationale for the design of anti-obesity therapies. Thyroid hormones play a key role in metabolic homeostasis through their interaction with thy...

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Bibliographic Details
Main Authors: Saira Hameed, Michael Patterson, Waljit S. Dhillo, Sofia A. Rahman, Yue Ma, Christopher Holton, Apostolos Gogakos, Giles S.H. Yeo, Brian Y.H. Lam, Joseph Polex-Wolf, Wiebke Fenske, Jimmy Bell, Jelena Anastasovska, Jacques Samarut, Stephen R. Bloom, J.H. Duncan Bassett, Graham R. Williams, James V. Gardiner
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Cell Reports
Subjects:
thyroid hormone
thyroid hormone receptor beta
hypothalamus
ventromedial hypothalamus
VMH
body weight
obesity
food intake
appetite
energy expenditure
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717307234

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http://www.sciencedirect.com/science/article/pii/S2211124717307234

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