Glutathione Metabolism Contributes to the Induction of Trained Immunity

The innate immune system displays heterologous memory characteristics, which are characterized by stronger responses to a secondary challenge. This phenomenon termed trained immunity relies on epigenetic and metabolic rewiring of innate immune cells. As reactive oxygen species (ROS) production has b...

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Bibliographic Details
Main Authors: Anaisa V. Ferreira, Valerie A.C.M. Koeken, Vasiliki Matzaraki, Sarantos Kostidis, Juan Carlos Alarcon-Barrera, L. Charlotte J. de Bree, Simone J.C.F.M. Moorlag, Vera P. Mourits, Boris Novakovic, Martin A. Giera, Mihai G. Netea, Jorge Domínguez-Andrés
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/5/971