The influence of the gut microbiome on BCG-induced trained immunity

by Martin Stražar, Vera P. Mourits, Valerie A. C. M. Koeken, L. Charlotte J. de Bree, Simone J. C. F. M. Moorlag, Leo A. B. Joosten, Reinout van Crevel, Hera Vlamakis, Mihai G. Netea, Ramnik J. Xavier
Published 2021-09-01

BCG-Induced Trained Immunity in Healthy Individuals: The Effect of Plasma Muramyl Dipeptide Concentrations

by Vera P. Mourits, Valerie A. C. M. Koeken, L. Charlotte J. de Bree, Simone J. C. F. M. Moorlag, Wern Cui Chu, Xiaoli Xu, Helga Dijkstra, Heidi Lemmers, Leo A. B. Joosten, Yue Wang, Reinout van Crevel, Mihai G. Netea
Published 2020-01-01

Glutathione Metabolism Contributes to the Induction of Trained Immunity

by Anaisa V. Ferreira, Valerie A.C.M. Koeken, Vasiliki Matzaraki, Sarantos Kostidis, Juan Carlos Alarcon-Barrera, L. Charlotte J. de Bree, Simone J.C.F.M. Moorlag, Vera P. Mourits, Boris Novakovic, Martin A. Giera, Mihai G. Netea, Jorge Domínguez-Andrés
Published 2021-04-01

The Immunological Factors Predisposing to Severe Covid-19 Are Already Present in Healthy Elderly and Men

by Gizem Kilic, Ozlem Bulut, Martin Jaeger, Rob ter Horst, Rob ter Horst, Valerie A. C. M. Koeken, Valerie A. C. M. Koeken, Simone J. C. F. M. Moorlag, Vera P. Mourits, Charlotte de Bree, Jorge Domínguez-Andrés, Leo A. B. Joosten, Mihai G. Netea, Mihai G. Netea
Published 2021-08-01

Lysine methyltransferase G9a is an important modulator of trained immunity

by Vera P Mourits, Jelmer H vanPuffelen, Boris Novakovic, Mariolina Bruno, Anaísa V Ferreira, Rob JW Arts, Laszlo Groh, Tania O Crișan, Jelle Zwaag, Elisa Jentho, Matthijs Kox, Peter Pickkers, Frank L van deVeerdonk, Sebastian Weis, Egbert Oosterwijk, Sita H Vermeulen, Mihai G Netea, Leo AB Joosten
Published 2021-01-01

BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils

by Simone J.C.F.M. Moorlag, Yessica Alina Rodriguez-Rosales, Joshua Gillard, Stephanie Fanucchi, Kate Theunissen, Boris Novakovic, Cynthia M. de Bont, Yutaka Negishi, Ezio T. Fok, Lydia Kalafati, Panayotis Verginis, Vera P. Mourits, Valerie A.C.M. Koeken, L. Charlotte J. de Bree, Ger J.M. Pruijn, Craig Fenwick, Reinout van Crevel, Leo A.B. Joosten, Irma Joosten, Hans Koenen, Musa M. Mhlanga, Dimitri A. Diavatopoulos, Triantafyllos Chavakis, Mihai G. Netea
Published 2020-11-01

Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study

by Simone J.C.F.M. Moorlag, Rosanne C. van Deuren, Cornelis H. van Werkhoven, Martin Jaeger, Priya Debisarun, Esther Taks, Vera P. Mourits, Valerie A.C.M. Koeken, L. Charlotte J. de Bree, Thijs ten Doesschate, Maartje C. Cleophas, Sanne Smeekens, Marije Oosting, Frank L. van de Veerdonk, Leo A.B. Joosten, Jaap ten Oever, Jos W.M. van der Meer, Nigel Curtis, Peter Aaby, Christine Stabell-Benn, Evangelos J. Giamarellos-Bourboulis, Marc Bonten, Reinout van Crevel, Mihai G. Netea
Published 2020-08-01

The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan

by Samuel T. Keating, Laszlo Groh, Charlotte D.C.C. van der Heijden, Hanah Rodriguez, Jéssica C. dos Santos, Stephanie Fanucchi, Jun Okabe, Harikrishnan Kaipananickal, Jelmer H. van Puffelen, Leonie Helder, Marlies P. Noz, Vasiliki Matzaraki, Yang Li, L. Charlotte J. de Bree, Valerie A.C.M. Koeken, Simone J.C.F.M. Moorlag, Vera P. Mourits, Jorge Domínguez-Andrés, Marije Oosting, Elianne P. Bulthuis, Werner J.H. Koopman, Musa Mhlanga, Assam El-Osta, Leo A.B. Joosten, Mihai G. Netea, Niels P. Riksen
Published 2020-04-01

Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease

by Xiaojing Chu, Martin Jaeger, Joep Beumer, Olivier B. Bakker, Raul Aguirre-Gamboa, Marije Oosting, Sanne P. Smeekens, Simone Moorlag, Vera P. Mourits, Valerie A. C. M. Koeken, Charlotte de Bree, Trees Jansen, Ian T. Mathews, Khoi Dao, Mahan Najhawan, Jeramie D. Watrous, Irma Joosten, Sonia Sharma, Hans J. P. M. Koenen, Sebo Withoff, Iris H. Jonkers, Romana T. Netea-Maier, Ramnik J. Xavier, Lude Franke, Cheng-Jian Xu, Leo A. B. Joosten, Serena Sanna, Mohit Jain, Vinod Kumar, Hans Clevers, Cisca Wijmenga, Mihai G. Netea, Yang Li
Published 2021-07-01

In vitro induction of trained immunity in adherent human monocytes

by Jorge Domínguez-Andrés, Rob J.W. Arts, Siroon Bekkering, Harsh Bahrar, Bastiaan A. Blok, L. Charlotte J. de Bree, Mariolina Bruno, Özlem Bulut, Priya A. Debisarun, Helga Dijkstra, Jéssica Cristina dos Santos, Anaísa V. Ferreira, Daniela Flores-Gomez, Laszlo A. Groh, Inge Grondman, Leonie Helder, Cor Jacobs, Liesbeth Jacobs, Trees Jansen, Gizem Kilic, Viola Klück, Valerie A.C.M. Koeken, Heidi Lemmers, Simone J.C.F.M. Moorlag, Vera P. Mourits, Jelmer H. van Puffelen, Katrin Rabold, Rutger J. Röring, Diletta Rosati, Helin Tercan, Julia van Tuijl, Jessica Quintin, Reinout van Crevel, Niels P. Riksen, Leo A.B. Joosten, Mihai G. Netea
Published 2021-03-01