A high-resolution map of segmental DNA copy number variation in the mouse genome.

Submicroscopic (less than 2 Mb) segmental DNA copy number changes are a recently recognized source of genetic variability between individuals. The biological consequences of copy number variants (CNVs) are largely undefined. In some cases, CNVs that cause gene dosage effects have been implicated in...

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Bibliographic Details
Main Authors: Timothy A Graubert, Patrick Cahan, Deepa Edwin, Rebecca R Selzer, Todd A Richmond, Peggy S Eis, William D Shannon, Xia Li, Howard L McLeod, James M Cheverud, Timothy J Ley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1761046?pdf=render