Rare Germline Pathogenic Variants Identified by Multigene Panel Testing and the Risk of Aggressive Prostate Cancer

Rare Germline Pathogenic Variants Identified by Multigene Panel Testing and the Risk of Aggressive Prostate Cancer

While gene panel sequencing is becoming widely used for cancer risk prediction, its clinical utility with respect to predicting aggressive prostate cancer (PrCa) is limited by our current understanding of the genetic risk factors associated with predisposition to this potentially lethal disease phen...

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Bibliographic Details
Main Authors: Tú Nguyen-Dumont, James G. Dowty, Robert J. MacInnis, Jason A. Steen, Moeen Riaz, Pierre-Antoine Dugué, Anne-Laure Renault, Fleur Hammet, Maryam Mahmoodi, Derrick Theys, Helen Tsimiklis, Gianluca Severi, Damien Bolton, Paul Lacaze, Robert Sebra, Eric Schadt, John McNeil, Graham G. Giles, Roger L. Milne, Melissa C. Southey
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
aggressive prostate cancer
gene panel testing
predisposition
genetic risk factors
Online Access:https://www.mdpi.com/2072-6694/13/7/1495

Internet

https://www.mdpi.com/2072-6694/13/7/1495

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