SmCL3, a gastrodermal cysteine protease of the human blood fluke Schistosoma mansoni.

Blood flukes of the genus Schistosoma are platyhelminth parasites that infect 200 million people worldwide. Digestion of nutrients from the host bloodstream is essential for parasite development and reproduction. A network of proteolytic enzymes (proteases) facilitates hydrolysis of host hemoglobin...

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Bibliographic Details
Main Authors: Jan Dvorák, Susan T Mashiyama, Mohammed Sajid, Simon Braschi, Melaine Delcroix, Eric L Schneider, Wilson H McKerrow, Mahmoud Bahgat, Elizabeth Hansell, Patricia C Babbitt, Charles S Craik, James H McKerrow, Conor R Caffrey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2685030?pdf=render