Fast effect size shrinkage software for beta-binomial models of allelic imbalance [version 2; peer review: 1 approved, 2 approved with reservations]
Allelic imbalance occurs when the two alleles of a gene are differentially expressed within a diploid organism and can indicate important differences in cis-regulation and epigenetic state across the two chromosomes. Because of this, the ability to accurately quantify the proportion at which each al...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2020-12-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/8-2024/v2 |