Fast effect size shrinkage software for beta-binomial models of allelic imbalance [version 2; peer review: 1 approved, 2 approved with reservations]

Allelic imbalance occurs when the two alleles of a gene are differentially expressed within a diploid organism and can indicate important differences in cis-regulation and epigenetic state across the two chromosomes. Because of this, the ability to accurately quantify the proportion at which each al...

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Bibliographic Details
Main Authors: Joshua P. Zitovsky, Michael I. Love
Format: Article
Language:English
Published: F1000 Research Ltd 2020-12-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-2024/v2