The effects of n-6 polyunsaturated fatty acid deprivation on the inflammatory gene response to lipopolysaccharide in the mouse hippocampus

The effects of n-6 polyunsaturated fatty acid deprivation on the inflammatory gene response to lipopolysaccharide in the mouse hippocampus

Abstract Background Neuroinflammation is thought to contribute to psychiatric and neurological disorders such as major depression and Alzheimer’s disease (AD). N-6 polyunsaturated fatty acids (PUFA) and molecules derived from them, including linoleic acid- and arachidonic acid-derived lipid mediator...

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Bibliographic Details
Main Authors: Shoug M. Alashmali, Lin Lin, Marc-Olivier Trépanier, Giulia Cisbani, Richard P. Bazinet
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Neuroinflammation
Subjects:
Neuroinflammation
Lipopolysaccharide
N-6 polyunsaturated fatty acids
mRNA
Hippocampus
Arachidonic acid
Online Access:http://link.springer.com/article/10.1186/s12974-019-1615-0

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http://link.springer.com/article/10.1186/s12974-019-1615-0

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