High-fat-diet-induced obesity causes an inflammatory and tumor-promoting microenvironment in the rat kidney

SUMMARY Obesity and concomitant comorbidities have emerged as public health problems of the first order. For instance, obese individuals have an increased risk for kidney cancer. However, direct mechanisms linking obesity with kidney cancer remain elusive. We hypothesized that diet-induced obesity (...

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Bibliographic Details
Main Authors: Kerstin Stemmer, Diego Perez-Tilve, Gayathri Ananthakrishnan, Anja Bort, Randy J. Seeley, Matthias H. Tschöp, Daniel R. Dietrich, Paul T. Pfluger
Format: Article
Language:English
Published: The Company of Biologists 2012-09-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/5/5/627