The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice.

The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice.

Toll-like receptors (TLR) and the downstream adaptor protein MyD88 are considered crucial for protective immunity during bacterial infections. Streptococcus (S.) pneumoniae is a human respiratory pathogen and a large majority of clinical pneumococcal isolates expresses an external polysaccharide cap...

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Bibliographic Details
Main Authors: Alex F de Vos, Mark C Dessing, Adriana J J Lammers, Alexander P N A de Porto, Sandrine Florquin, Onno J de Boer, Regina de Beer, Sanne Terpstra, Hester J Bootsma, Peter W Hermans, Cornelis van 't Veer, Tom van der Poll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4336322?pdf=render

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http://europepmc.org/articles/PMC4336322?pdf=render

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