COSMO: A dynamic programming algorithm for multicriteria codon optimization

COSMO: A dynamic programming algorithm for multicriteria codon optimization

Codon optimization in protein-coding sequences (CDSs) is a widely used technique to promote the heterologous expression of target genes. In codon optimization, a combinatorial space of nucleotide sequences that code a given amino acid sequence and take into account user-prescribed forbidden sequence...

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Bibliographic Details
Main Authors: Akito Taneda, Kiyoshi Asai
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Constraints
Codon adaptation index
Codon pair bias
Hidden stop codon
Multi-objective genetic algorithm
Codon optimization/deoptimization
Online Access:http://www.sciencedirect.com/science/article/pii/S200103702030324X

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http://www.sciencedirect.com/science/article/pii/S200103702030324X

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