Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene

Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene

Abstract Frontotemporal Lobar Degeneration (FTLD) encompasses certain related neurodegenerative disorders which alter behaviour, personality and language. Heterogeneous ribonuclear proteins (hnRNPs) maintain RNA metabolism and changes in their function may underpin the pathogenesis of FTLD. Immunost...

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Bibliographic Details
Main Authors: Yvonne S. Davidson, Louis Flood, Andrew C. Robinson, Yoshihiro Nihei, Kohji Mori, Sara Rollinson, Anna Richardson, Bridget C. Benson, Matthew Jones, Julie S. Snowden, Stuart Pickering-Brown, Christian Haass, Tammaryn Lashley, David M. A. Mann
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Acta Neuropathologica Communications
Subjects:
Frontotemporal Lobar Degeneration
Motor neuron disease
Heterogeneous ribonuclear proteins
C9orf72 gene
Dipeptide repeat proteins
Online Access:http://link.springer.com/article/10.1186/s40478-017-0437-5

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http://link.springer.com/article/10.1186/s40478-017-0437-5

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