The Route of Early T Cell Development: Crosstalk between Epigenetic and Transcription Factors

The Route of Early T Cell Development: Crosstalk between Epigenetic and Transcription Factors

Hematopoietic multipotent progenitors seed the thymus and then follow consecutive developmental stages until the formation of mature T cells. During this process, phenotypic changes of T cells entail stage-specific transcriptional programs that underlie the dynamic progression towards mature lymphoc...

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Bibliographic Details
Main Authors: Veronica Della Chiara, Lucia Daxinger, Frank J. T. Staal
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
T cell development
T cell commitment
transcription factors
epigenetic regulators
chromatin modifiers
Tcf1
Online Access:https://www.mdpi.com/2073-4409/10/5/1074

Internet

https://www.mdpi.com/2073-4409/10/5/1074

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