Systematic Approaches towards the Development of Host-Directed Antiviral Therapeutics

Systematic Approaches towards the Development of Host-Directed Antiviral Therapeutics

Since the onset of antiviral therapy, viral resistance has compromised the clinical value of small-molecule drugs targeting pathogen components. As intracellular parasites, viruses complete their life cycle by hijacking a multitude of host-factors. Aiming at the latter rather than the pathogen direc...

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Bibliographic Details
Main Authors: James P. Snyder, Richard K. Plemper, Pahk Thepchatri, Andrew Prussia
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:International Journal of Molecular Sciences
Subjects:
genome-wide screening
pathway analysis
HIV
Influenza virus
bioinformatics
antiviral
target identification
RNAi
siRNA
Online Access:http://www.mdpi.com/1422-0067/12/6/4027/

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http://www.mdpi.com/1422-0067/12/6/4027/

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