TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia

TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia

Proteinaceous aggregates are major hallmarks of several neurodegenerative diseases. Aggregates of post-translationally modified transactive response (TAR)-DNA binding protein 43 (TDP-43) in cytoplasmic inclusion bodies are characteristic features in frontotemporal dementia (FTD) and amyotrophic late...

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Bibliographic Details
Main Authors: Mauro Montalbano, Salome McAllen, Filippa Lo Cascio, Urmi Sengupta, Stephanie Garcia, Nemil Bhatt, Anna Ellsworth, Eric A. Heidelman, Omar D. Johnson, Samantha Doskocil, Rakez Kayed
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Neurobiology of Disease
Subjects:
TDP-43
Tau
Aggregation
Oligomer
Tauopathies
Neurodegeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120304058

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http://www.sciencedirect.com/science/article/pii/S0969996120304058

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