Adiponectin Limits IFN-γ and IL-17 Producing CD4 T Cells in Obesity by Restraining Cell Intrinsic Glycolysis

Adiponectin Limits IFN-γ and IL-17 Producing CD4 T Cells in Obesity by Restraining Cell Intrinsic Glycolysis

Compared to the innate immune system, the contribution of the adaptive immune response during obesity and insulin resistance is still not completely understood. Here we demonstrate that high fat diet (HFD) increases the frequencies of activated CD4+ and CD8+ T cells and frequencies of T cells positi...

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Bibliographic Details
Main Authors: Jayagopi Surendar, Stefan J. Frohberger, Indulekha Karunakaran, Vanessa Schmitt, Wiebke Stamminger, Anna-Lena Neumann, Christoph Wilhelm, Achim Hoerauf, Marc P. Hübner
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
adiponectin
obesity
T cells
inflammation
filariasis
helminth
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02555/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02555/full

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