RNAi-Mediated Specific Gene Silencing as a Tool for the Discovery of New Drug Targets in Giardia lamblia; Evaluation Using the NADH Oxidase Gene

RNAi-Mediated Specific Gene Silencing as a Tool for the Discovery of New Drug Targets in Giardia lamblia; Evaluation Using the NADH Oxidase Gene

The microaerophilic protozoan Giardia lamblia is the agent causing giardiasis, an intestinal parasitosis of worldwide distribution. Different pharmacotherapies have been employed against giardiasis; however, side effects in the host and reports of drug resistant strains generate the need to develop...

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Bibliographic Details
Main Authors: Jaime Marcial-Quino, Saúl Gómez-Manzo, Francisco Fierro, Yadira Rufino-González, Daniel Ortega-Cuellar, Edgar Sierra-Palacios, America Vanoye-Carlo, Abigail González-Valdez, Angélica Torres-Arroyo, Jesús Oria-Hernández, Horacio Reyes-Vivas
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Genes
Subjects:
Giardia
NADH oxidase
drug targets
RNAi
siRNA
stem-loop RT-qPCR
Online Access:https://www.mdpi.com/2073-4425/8/11/303

Internet

https://www.mdpi.com/2073-4425/8/11/303

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