Structures and biological activities of novel phosphatidylethanolamine lipids of Porphyromonas gingivalis

Structures and biological activities of novel phosphatidylethanolamine lipids of Porphyromonas gingivalis

The Gram-negative periodontal pathogen Porphyromonas gingivalis synthesizes several classes of novel phosphorylated complex lipids, including the recently characterized phosphorylated dihydroceramides. These sphingolipids promote the interleukin-1 (IL-1)-mediated secretion of inflammatory mediators...

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Bibliographic Details
Main Authors: Frank C. Nichols, Birgit Riep, Jiyoung Mun, Martha D. Morton, Toshihisa Kawai, Floyd E. Dewhirst, Michael B. Smith
Format: Article
Language:English
Published: Elsevier 2006-04-01
Series:Journal of Lipid Research
Subjects:
interleukin-1β
prostaglandin E2
gingival fibroblast
long-chain base
gas chromatography-mass spectrometry
electrospray tandem mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520332818

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http://www.sciencedirect.com/science/article/pii/S0022227520332818

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