Cardiac-Restricted Expression of VCP/TER94 RNAi or Disease Alleles Perturbs Drosophila Heart Structure and Impairs Function

Valosin-containing protein (VCP) is a highly conserved mechanoenzyme that helps maintain protein homeostasis in all cells and serves specialized functions in distinct cell types. In skeletal muscle, it is critical for myofibrillogenesis and atrophy. However, little is known about VCP’s role(s) in th...

Full description

Bibliographic Details
Main Authors: Meera C. Viswanathan, Anna C. Blice-Baum, Tzu-Kang Sang, Anthony Cammarato
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
p97
Online Access:http://www.mdpi.com/2308-3425/3/2/19