Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty

Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty

The neglected tropical disease, schistosomiasis, is caused by trematode blood flukes of the <i>Schistosoma</i> genus and infects approximately 200 million people worldwide. With just one partially effective drug available for disease treatment, new drugs are urgently needed. Herein, a se...

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Bibliographic Details
Main Authors: Snigdha Singh, Nelly El-Sakkary, Danielle E. Skinner, Prem Prakash Sharma, Sabine Ottilie, Yevgeniya Antonova-Koch, Prashant Kumar, Elizabeth Winzeler, Poonam, Conor R. Caffrey, Brijesh Rathi
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceuticals
Subjects:
phthalimide
benzimidazole
<i>schistosoma</i>
click chemistry
anti-schistosomal activity
tropical disease
drug discovery
Online Access:https://www.mdpi.com/1424-8247/13/2/25

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https://www.mdpi.com/1424-8247/13/2/25

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