Model‐based evaluation of image‐guided fractionated whole‐brain radiation therapy in pediatric diffuse intrinsic pontine glioma xenografts

Model‐based evaluation of image‐guided fractionated whole‐brain radiation therapy in pediatric diffuse intrinsic pontine glioma xenografts

Abstract Radiation therapy (RT) is currently the standard treatment for diffuse intrinsic pontine glioma (DIPG), the most common cause of death in children with brain cancer. A pharmacodynamic model was developed to describe the radiation‐induced tumor shrinkage and overall survival in mice bearing...

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Bibliographic Details
Main Authors: Hillary R. Husband, Olivia Campagne, Chen He, Xiaoyan Zhu, Brandon M. Bianski, Suzanne J. Baker, Anang A. Shelat, Christopher L. Tinkle, Clinton F. Stewart
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12627

Internet

https://doi.org/10.1002/psp4.12627

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