Robust Classification of Small-Molecule Mechanism of Action Using a Minimalist High-Content Microscopy Screen and Multidimensional Phenotypic Trajectory Analysis.

by Nathaniel R Twarog, Jonathan A Low, Duane G Currier, Greg Miller, Taosheng Chen, Anang A Shelat
Published 2016-01-01

Data vignettes for the application of response surface models in drug combination analysis

by Nathaniel R. Twarog, Nancy E. Martinez, Jessica Gartrell, Jia Xie, Christopher L. Tinkle, Anang A. Shelat
Published 2021-10-01

Virtual-screening workflow tutorials and prospective results from the Teach-Discover-Treat competition 2014 against malaria [version 2; referees: 3 approved]

by Sereina Riniker, Gregory A. Landrum, Floriane Montanari, Santiago D. Villalba, Julie Maier, Johanna M. Jansen, W. Patrick Walters, Anang A. Shelat
Published 2018-02-01

Virtual-screening workflow tutorials and prospective results from the Teach-Discover-Treat competition 2014 against malaria [version 1; referees: 2 approved]

by Sereina Riniker, Gregory A. Landrum, Floriane Montanari, Santiago D. Villalba, Julie Maier, Johanna M. Jansen, W. Patrick Walters, Anang A. Shelat
Published 2017-07-01

Model‐based evaluation of image‐guided fractionated whole‐brain radiation therapy in pediatric diffuse intrinsic pontine glioma xenografts

by Hillary R. Husband, Olivia Campagne, Chen He, Xiaoyan Zhu, Brandon M. Bianski, Suzanne J. Baker, Anang A. Shelat, Christopher L. Tinkle, Clinton F. Stewart
Published 2021-06-01

Identification of small molecule activators of BMP signaling.

by Karen Vrijens, Wenwei Lin, Jimmy Cui, Dana Farmer, Jonathan Low, Elodie Pronier, Fu-Yue Zeng, Anang A Shelat, Kiplin Guy, Michael R Taylor, Taosheng Chen, Martine F Roussel
Published 2013-01-01

MAIP: a web service for predicting blood‐stage malaria inhibitors

by Nicolas Bosc, Eloy Felix, Ricardo Arcila, David Mendez, Martin R. Saunders, Darren V. S. Green, Jason Ochoada, Anang A. Shelat, Eric J. Martin, Preeti Iyer, Ola Engkvist, Andreas Verras, James Duffy, Jeremy Burrows, J. Mark F. Gardner, Andrew R. Leach
Published 2021-02-01

Targeting the DNA Repair Pathway in Ewing Sarcoma

by Elizabeth Stewart, Ross Goshorn, Cori Bradley, Lyra M. Griffiths, Claudia Benavente, Nathaniel R. Twarog, Gregory M. Miller, William Caufield, Burgess B. Freeman III, Armita Bahrami, Alberto Pappo, Jianrong Wu, Amos Loh, Åsa Karlström, Chris Calabrese, Brittney Gordon, Lyudmila Tsurkan, M. Jason Hatfield, Philip M. Potter, Scott E. Snyder, Suresh Thiagarajan, Abbas Shirinifard, Andras Sablauer, Anang A. Shelat, Michael A. Dyer
Published 2014-11-01

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma

by Chen He, Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin, Nathaniel Twarog, Laura D. Hover, Chang-Hyuk Kwon, Lawryn H. Kasper, Junyuan Zhang, Xiaoyu Li, James Dalton, Barbara Jonchere, Kimberly S. Mercer, Duane G. Currier, William Caufield, Yingzhe Wang, Jia Xie, Alberto Broniscer, Cynthia Wetmore, Santhosh A. Upadhyaya, Ibrahim Qaddoumi, Paul Klimo, Frederick Boop, Amar Gajjar, Jinghui Zhang, Brent A. Orr, Giles W. Robinson, Michelle Monje, Burgess B. Freeman III, Martine F. Roussel, Paul A. Northcott, Taosheng Chen, Zoran Rankovic, Gang Wu, Jason Chiang, Christopher L. Tinkle, Anang A. Shelat, Suzanne J. Baker
Published 2021-07-01