A protocol for high-throughput screening of histone lysine demethylase 4 inhibitors using TR-FRET assay

by Qiong Wu, Wenwei Lin, Zhen-Mei Li, Zoran Rankovic, Stephen W. White, Taosheng Chen, Jun Yang
Published 2021-09-01

Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases

by Seung Wook Yang, Xin Huang, Wenwei Lin, Jaeki Min, Darcie J. Miller, Anand Mayasundari, Patrick Rodrigues, Elizabeth C. Griffith, Clifford T. Gee, Lei Li, Wei Li, Richard E. Lee, Zoran Rankovic, Taosheng Chen, Patrick Ryan Potts
Published 2020-10-01

17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma

by Shivendra Singh, Ahmed Abu-Zaid, Wenwei Lin, Jonathan Low, Alireza Abdolvahabi, Hongjian Jin, Qiong Wu, Bailey Cooke, Jie Fang, John Bowling, Sivaraja Vaithiyalingam, Duane Currier, Mi-Kyung Yun, Dinesh M. Fernando, Julie Maier, Heather Tillman, Purva Bulsara, Zhaohua Lu, Sourav Das, Anang Shelat, Zhenmei Li, Brandon Young, Richard Lee, Zoran Rankovic, Andrew J. Murphy, Stephen W. White, Andrew M. Davidoff, Taosheng Chen, Jun Yang
Published 2021-01-01

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma

by Chen He, Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin, Nathaniel Twarog, Laura D. Hover, Chang-Hyuk Kwon, Lawryn H. Kasper, Junyuan Zhang, Xiaoyu Li, James Dalton, Barbara Jonchere, Kimberly S. Mercer, Duane G. Currier, William Caufield, Yingzhe Wang, Jia Xie, Alberto Broniscer, Cynthia Wetmore, Santhosh A. Upadhyaya, Ibrahim Qaddoumi, Paul Klimo, Frederick Boop, Amar Gajjar, Jinghui Zhang, Brent A. Orr, Giles W. Robinson, Michelle Monje, Burgess B. Freeman III, Martine F. Roussel, Paul A. Northcott, Taosheng Chen, Zoran Rankovic, Gang Wu, Jason Chiang, Christopher L. Tinkle, Anang A. Shelat, Suzanne J. Baker
Published 2021-07-01