Urinary proteomics links keratan sulfate degradation and lysosomal enzymes to early type 1 diabetes.

Urinary proteomics links keratan sulfate degradation and lysosomal enzymes to early type 1 diabetes.

Diabetes is the leading cause of end-stage renal disease worldwide. Our understanding of the early kidney response to chronic hyperglycemia remains incomplete. To address this, we first investigated the urinary proteomes of otherwise healthy youths with and without type 1 diabetes and subsequently e...

Full description

Bibliographic Details
Main Authors: Julie A D Van, Sergi Clotet-Freixas, Anne-Christin Hauschild, Ihor Batruch, Igor Jurisica, Yesmino Elia, Farid H Mahmud, Etienne Sochett, Eleftherios P Diamandis, James W Scholey, Ana Konvalinka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233639

Internet

https://doi.org/10.1371/journal.pone.0233639

Similar Items