Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.

Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.

The cytosolic glutathione transferase (cytGST) superfamily comprises more than 13,000 nonredundant sequences found throughout the biosphere. Their key roles in metabolism and defense against oxidative damage have led to thousands of studies over several decades. Despite this attention, little is kno...

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Bibliographic Details
Main Authors: Susan T Mashiyama, M Merced Malabanan, Eyal Akiva, Rahul Bhosle, Megan C Branch, Brandan Hillerich, Kevin Jagessar, Jungwook Kim, Yury Patskovsky, Ronald D Seidel, Mark Stead, Rafael Toro, Matthew W Vetting, Steven C Almo, Richard N Armstrong, Patricia C Babbitt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3995644?pdf=render

Internet

http://europepmc.org/articles/PMC3995644?pdf=render

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