An integrative genomic and transcriptomic analysis reveals potential targets associated with cell proliferation in uterine leiomyomas.

Uterine Leiomyomas (ULs) are the most common benign tumours affecting women of reproductive age. ULs represent a major problem in public health, as they are the main indication for hysterectomy. Approximately 40-50% of ULs have non-random cytogenetic abnormalities, and half of ULs may have copy numb...

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Bibliographic Details
Main Authors: Priscila Daniele Ramos Cirilo, Fábio Albuquerque Marchi, Mateus de Camargo Barros Filho, Rafael Malagoli Rocha, Maria Aparecida Custódio Domingues, Igor Jurisica, Anagloria Pontes, Silvia Regina Rogatto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3587425?pdf=render