SGLT1 is required for the survival of triple‐negative breast cancer cells via potentiation of EGFR activity

SGLT1 is required for the survival of triple‐negative breast cancer cells via potentiation of EGFR activity

Sodium/glucose cotransporter 1 (SGLT1), an essential active glucose transport protein that helps maintain high intracellular glucose levels, was previously shown to interact with epidermal growth factor receptor (EGFR); the SGLT1–EGFR interaction maintains intracellular glucose levels to promote sur...

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Bibliographic Details
Main Authors: Huiquan Liu, Ayse Ertay, Ping Peng, Juanjuan Li, Dian Liu, Hua Xiong, Yanmei Zou, Hong Qiu, David Hancock, Xianglin Yuan, Wei‐Chien Huang, Rob M. Ewing, Julian Downward, Yihua Wang
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Molecular Oncology
Subjects:
EGFR
SGLT1
triple‐negative breast cancer
Online Access:https://doi.org/10.1002/1878-0261.12530

Internet

https://doi.org/10.1002/1878-0261.12530

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