Ancestry-specific predisposing germline variants in cancer

Abstract Background Distinct prevalence of inherited genetic predisposition may partially explain the difference of cancer risks across ancestries. Ancestry-specific analyses of germline genomes are required to inform cancer genetic risk and prognosis of diverse populations. Methods We conducted ana...

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Bibliographic Details
Main Authors: Ninad Oak, Andrew D. Cherniack, R. Jay Mashl, TCGA Analysis Network, Fred R. Hirsch, Li Ding, Rameen Beroukhim, Zeynep H. Gümüş, Sharon E. Plon, Kuan-lin Huang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-020-00744-3