Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo

Summary: Astrocytes from familial amyotrophic lateral sclerosis (ALS) patients or transgenic mice are toxic specifically to motor neurons (MNs). It is not known if astrocytes from sporadic ALS (sALS) patients cause MN degeneration in vivo and whether the effect is specific to MNs. By transplanting s...

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Bibliographic Details
Main Authors: Kun Qian, Hailong Huang, Andrew Peterson, Baoyang Hu, Nicholas J. Maragakis, Guo-li Ming, Hong Chen, Su-Chun Zhang
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117300917