Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.

Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.

CD4+ T cells subsets have a wide range of important helper and regulatory functions in the immune system. Several studies have specifically suggested that circulating effector CD4+ T cells may play a direct role in control of HIV replication through cytolytic activity or autocrine β-chemokine produc...

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Bibliographic Details
Main Authors: Marcus Buggert, Son Nguyen, Laura M McLane, Maria Steblyanko, Nadia Anikeeva, Dominic Paquin-Proulx, Perla M Del Rio Estrada, Yuria Ablanedo-Terrazas, Kajsa Noyan, Morgan A Reuter, Korey Demers, Johan K Sandberg, Michael A Eller, Hendrik Streeck, Marianne Jansson, Piotr Nowak, Anders Sönnerborg, David H Canaday, Ali Naji, E John Wherry, Merlin L Robb, Steven G Deeks, Gustavo Reyes-Teran, Yuri Sykulev, Annika C Karlsson, Michael R Betts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006973

Internet

https://doi.org/10.1371/journal.ppat.1006973

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