The Environment Shapes the Inner Vestibule of LeuT.

The Environment Shapes the Inner Vestibule of LeuT.

Human neurotransmitter transporters are found in the nervous system terminating synaptic signals by rapid removal of neurotransmitter molecules from the synaptic cleft. The homologous transporter LeuT, found in Aquifex aeolicus, was crystallized in different conformations. Here, we investigated the...

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Main Authors: Azmat Sohail, Kumaresan Jayaraman, Santhoshkannan Venkatesan, Kamil Gotfryd, Markus Daerr, Ulrik Gether, Claus J Loland, Klaus T Wanner, Michael Freissmuth, Harald H Sitte, Walter Sandtner, Thomas Stockner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1005197

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https://doi.org/10.1371/journal.pcbi.1005197

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